Malic acid

Malic acid is an intermediate in the citric acid cycle. Malic acid is found in apples.

Fibromyalgia

• 2009, Management of Fibromyalgia: Rationale for the Use of Magnesium and Malic Acid (non-blinded)
  • While these results are promising, a subsequent double-blind crossover study of primary fibromyalgia patients who received 300 mg magnesium and 1200 mg malic acid or placebo in random order for four weeks, each with a two-week washout period in between, failed to find significant improvements in pain, tenderness, and functional or psychological measures

blinded trial A clinical trial is blinded if either the participants or the researchers don't know which treatment group they are allocated to until after the results are interpreted. (Learn more: www.nottingham.ac.uk)

double blinded trial A clinical trial is double blinded if neither the participants nor the researchers know which treatment group they are allocated to until after the results are interpreted. This reduces bias. (Learn more: www.nottingham.ac.uk)